HYDROXYZINE

INDICATION AND DOSAGE OF HYDROXYZINE

What It Is

Hydroxyzine is a first-generation antihistamine with anxiolytic, sedative, and antiemetic properties. It is commonly used to treat a range of conditions, including anxiety, allergies, and nausea. Hydroxyzine is known for its ability to produce a calming effect, making it a useful medication in both psychiatric and non-psychiatric settings.

Dosage Forms and Strengths

Hydroxyzine is available in various dosage forms, including:

  1. Tablets: Typically available in strengths of 10 mg, 25 mg, and 50 mg.
  2. Capsules: Usually found in 25 mg and 50 mg strengths.
  3. Oral Suspension: Available as a liquid form with a concentration of 10 mg/5 mL.
  4. Intramuscular Injection: Hydroxyzine can be administered via injection, generally in a concentration of 50 mg/mL.

Brand and Generic Names

Hydroxyzine is marketed under several brand names, including:

  • Vistaril
  • Atarax

The generic name for the drug is hydroxyzine.

Indications for Use

Hydroxyzine is prescribed for a variety of medical conditions, including:

  • Anxiety: It is used as a short-term treatment for anxiety and tension.
  • Allergies: Hydroxyzine helps relieve symptoms of allergic reactions, such as itching and hives.
  • Nausea and Vomiting: It is used to manage nausea and vomiting associated with various conditions.
  • Preoperative Sedation: Hydroxyzine is sometimes administered before surgery to reduce anxiety and induce sedation.
  • Insomnia: It can be used to help with sleep disturbances due to its sedative effects.

Mechanism of Action

Hydroxyzine works primarily as an antihistamine by blocking the H1 receptors in the central nervous system and peripheral tissues. This action reduces the effects of histamine, a chemical involved in allergic reactions. Additionally, hydroxyzine exerts its anxiolytic and sedative effects through its action on the central nervous system, although the precise mechanisms are not fully understood.

Administration and Dosage

The dosage of hydroxyzine varies based on the condition being treated, the patient's age, and their overall health. General guidelines include:

  • Anxiety: For adults, the usual oral dose is 50-100 mg up to four times daily. For children, the dosage is typically based on body weight.
  • Allergies: Adults usually take 25 mg to 50 mg three to four times daily. For children, dosing is again based on weight.
  • Nausea: The typical oral dose is 25 mg to 100 mg every 4 to 6 hours as needed.
  • Preoperative Sedation: The intramuscular dose is generally 50-100 mg administered about an hour before surgery.

Effects and Precautions

Hydroxyzine may cause several side effects, including:

  • Drowsiness: The most common side effect, which can affect daily activities.
  • Dry Mouth: A frequent side effect due to the anticholinergic properties of hydroxyzine.
  • Dizziness: May occur, especially in older adults.
  • Constipation: Another common anticholinergic effect.
  • Blurred Vision: Can result from the drug’s anticholinergic activity.

Precautions should be taken for individuals with:

  • Glaucoma: Hydroxyzine can exacerbate symptoms of narrow-angle glaucoma.
  • Prostate Enlargement: The drug can worsen urinary retention.
  • Severe Liver Disease: Dose adjustments may be necessary.

Hydroxyzine should be used cautiously in combination with other central nervous system depressants, as it may enhance sedative effects.

Conclusion

Hydroxyzine is a versatile medication used for treating anxiety, allergies, nausea, and other conditions due to its antihistamine and sedative properties. Available in various forms and strengths, it is effective for short-term relief but requires careful dosing and monitoring due to its side effects and interactions. Patients should use hydroxyzine under the guidance of a healthcare provider to ensure its efficacy and safety.

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HYDROXYZINE TAB 10 MG 10 UNITS TARAXIN T.O.CHEMICAL (excluded of 20 USD Postage fee/order)
Hydroxyzine is a medication that is used for various indications, including the treatment of anxiety, itching, allergies, and as a sedative.
3.87 USD
HYDROXYZINE TAB 25 MG 10 UNITS TARAXIN T.O.CHEMICAL (excluded of 20 USD Postage fee/order)
Hydroxyzine is a medication that is used for various indications, including the treatment of anxiety, itching, allergies, and as a sedative.
4.40 USD

HYDROXYZINE TAB 10 MG 10 UNITS TARAXIN T.O.CHEMICAL (excluded of 20 USD Postage fee/order) (TARAXIN)

Hydroxyzine is a medication that is used for various indications, including the treatment of anxiety, itching, allergies, and as a sedative.
3.87 USD

HYDROXYZINE TAB 25 MG 10 UNITS TARAXIN T.O.CHEMICAL (excluded of 20 USD Postage fee/order) (TARAXIN)

Hydroxyzine is a medication that is used for various indications, including the treatment of anxiety, itching, allergies, and as a sedative.
4.40 USD
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