CILOSTAZOL TAB 100 MG 30 UNITS BESTAZOL 100 BERLIN PHARMA

$77.00
Qty:

CILOSTAZOL TAB 100 MG 30 UNITS BESTAZOL 50 BERLIN PHARMA

Contents Cilostazol Indications/Uses Ischemic symptoms, including ulceration, pain & coldness of the extremities, in chronic arterial occlusion. Prevention of recurrence of cerebral infarction (excluding cardiogenic cerebral embolism). Dosage/Direction for Use Adult 100 mg bid. Co-administration w/ CYP3A4 inhibitors eg, ketoconazole, itraconazole, erythromycin & diltiazem; CYP2C19 inhibitors eg, omeprazole Reduce dose to 50 mg bid. Administration Should be taken on an empty stomach: Take at least 30 min before or 2 hr after meals. Contraindications Hypersensitivity. CHF, hemostatic disorders or active bleeding (eg, bleeding peptic ulcer & intracranial bleeding). Pregnancy. Special Precautions History of hypersensitivity. May increase heart rate, premature ventricular contractions & tachycardia. Do not use if symptoms of CHF are present. CV risk on prolonged treatment. Rare cases of thrombocytopenia or leukopenia. Patients w/ cerebral infarction. Control BP during treatment in patients w/ cerebral infarction w/ high BP. Withhold treatment for 4-6 half-lives prior to elective surgical procedures. Check bleeding times during coadministration w/ clopidogrel. Patients receiving other platelet aggregation inhibitors, CYP3A4 inhibitors (eg, ketoconazole, itraconazole, erythromycin & diltiazem) or CYP2C19 inhibitors (eg, omeprazole). Moderate or severe hepatic or severe renal impairment (CrCl <25 mL/min). Lactation. Childn. Elderly. Adverse Reactions Palpitation, tachycardia, dizziness, headache, vertigo, abdominal pain, abnormal stools, diarrhea, dyspepsia, flatulence, nausea, peripheral edema, musculoskeletal, back pain, myalgia, increased cough, pharyngitis, rhinitis, infection. Drug Interactions Increased inhibition of platelet aggregation w/ aspirin. May elevate plasma conc of certain HMG-CoA reductase inhibitors. Decreased Css,max & AUC w/ lovastatin. Clopidogrel. Increased plasma conc & decreased clearance w/ other CYP3A4 isoenzyme inhibitors including certain azole antifungals (eg, fluconazole, itraconazole, ketoconazole, miconazole), certain macrolide antibiotics (eg, erythromycin or clarithromycin but not azithromycin), certain SSRIs (eg, fluoxetine, fluvoxamine, nefazodone, sertraline), certain antiretroviral agents (eg, indinavir), metronidazole, diltiazem & danazol. Decreased metabolism w/ erythromycin & other macrolide antibiotics. Increased plasma conc by diltiazem. Metabolism may be inhibited & plasma conc may be elevated by omeprazole. Increased Cmax w/ grapefruit juice. Synergistic effects w/ Ginkgo biloba. Decreased systemic exposure w/ tobacco smoking. Description View Bestazol 50/Bestazol 100 description for details of the chemical structure and excipients (inactive components). MIMS Class Anticoagulants, Antiplatelets & Fibrinolytics (Thrombolytics) ATC Classification B01AC23 - cilostazol ; Belongs to the class of platelet aggregation inhibitors excluding heparin. Used in the treatment of thrombosis. Thai FDA Category D

  • Model: BESTAZOL 100
  • Brand: BERLIN PHARMA

Write Review

Note: Do not use HTML in the text.

GTM