UMECLIDINIUM BROMIDE VILANTEROL TRIFENATATE INHALER POWDER 30 DOSES 1 UNITS ANORO ELLIPTA GLAXOSMITHKLINE

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UMECLIDINIUM BROMIDE VILANTEROL TRIFENATATE INHALER POWDER 30 DOSES 1 UNITS ANORO ELLIPTA GLAXOSMITHKLINE

Contents Per dose Umeclidinium 62.5 mcg (equiv to 74.2 mcg umeclidinium Br), vilanterol 25 mcg (as trifenatate) Indications/Uses Maintenance bronchodilator treatment to relieve symptoms associated w/ COPD. Dosage/Direction for Use Adult Recommended & max dose: 1 inhalation once daily at the same time each day. Contraindications Patients w/ severe milk-protein allergy. Special Precautions Not recommended for patients w/ asthma; relief of acute symptoms, ie, as rescue therapy for treatment of acute episodes of bronchospasm. Discontinue use if life-threatening paradoxical bronchospasm occurs. Severe CV disease. Narrow-angle glaucoma or urinary retention. Pregnancy & lactation. Adverse Reactions UTI, sinusitis, nasopharyngitis, pharyngitis, URTI; cough, oropharyngeal pain; constipation, dry mouth. Drug Interactions Effects may be weakened or antagonized w/ β-adrenergic blockers. Potential increase in systemic exposure w/ strong CYP3A4 inhibitors eg, ketoconazole. MIMS Class Antiasthmatic & COPD Preparations ATC Classification R03AL03 - vilanterol and umeclidinium bromide ; Belongs to the class of combination of adrenergics with anticholinergics, that may also include a corticosteroid. Used in the treatment of obstructive airway diseases. Thai FDA Category S

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