Indication:

Trazodone is an antidepressant medication that belongs to a group of medicines called serotonin modulators. It is used for the treatment of major depressive disorder (MDD) in adults. Trazodone is also commonly used off-label to treat insomnia, although the benefit of taking trazodone for insomnia is not well established. It is important to note that trazodone is not approved for use in pediatric patients and should be used with caution in older adults.

Dosage:

• For the treatment of depression, the usual initial dose of trazodone is 150 mg per day, which may be initiated at a lower dose of 100 mg to reduce the chance of side effects. The dosage may be adjusted based on the individual's response to the medication, and in some cases, the doctor may prescribe up to 300 mg a day for depression.
• For the treatment of anxiety, the usual dose of trazodone is 75 mg daily, with the potential for the dose to be adjusted based on individual response.
• When used off-label for insomnia, studies suggest that a low dose of trazodone between 25 mg and 100 mg may be effective for improving sleep. The typical trazodone dosage for sleep is 25 mg to 100 mg before bedtime. It's important to consult with a healthcare provider before taking trazodone for sleep regarding potential side effects, dosage, and interactions.

It's crucial to take trazodone only as directed by a healthcare professional and not to take more of it, take it more often, or take it for a longer time than prescribed. Additionally, trazodone should be stored at room temperature and should not be used in pediatric patients without proper medical guidance.

As with any medication, it is advisable to consult with a healthcare professional for personalized advice and guidance regarding the indication and dosage of trazodone based on the specific medical condition.