Indication:

• Ciclosporin, also known as cyclosporine, is indicated for various medical conditions, including:
  • Prevention of organ rejection in kidney, liver, and heart allogeneic transplants.
  • Treatment of severe active rheumatoid arthritis when the disease has not adequately responded to methotrexate.
  • Treatment of psoriasis.
  • Treatment of persistent nummular keratitis following adenoviral keratoconjunctivitis.
  • Treatment of dry eyes caused by Sjögren's syndrome and meibomian gland dysfunction.

Dosage:

• The dosage of ciclosporin may vary depending on the specific condition being treated. It is important to follow the instructions provided by your healthcare provider and the product labeling.
• The initial dosage of ciclosporin for organ transplant recipients depends on the organ being transplanted and any other medications being taken. The dosage is typically adjusted based on therapeutic drug monitoring and individual patient response.
• For the treatment of rheumatoid arthritis, the initial dosage is usually 1.25 mg/kg orally twice daily, which may be increased if necessary, up to a maximum of 4 mg/kg per day.
• For the treatment of psoriasis, the dosage may vary depending on the severity of the condition and individual patient response. The initial dosage is typically 2.5 mg/kg per day, divided into two doses, and may be increased up to a maximum of 4 mg/kg per day.
• It is important to take ciclosporin exactly as prescribed by your doctor and not to exceed the recommended dosage.

Please note that the information provided here is based on the search results and should not replace the advice of a healthcare professional. Always consult with your doctor or pharmacist for personalized dosage instructions and recommendations.